Pre-formulation Analysis

Preformulation studies have a significant part to play in anticipating formulation problems and identifying logical paths in both liquid and solid dosage form development. The Centre offers a complete preformulation analytical package that is tailored to the requirements of the client.

Typically, our preformulation analytical package can include any of the following:

• Solubility (aqueous, solvent and biorelevant media), pKa, logP/D;
• Moisture content, sorption analysis;
• Thermal analysis (thermal behaviour, melting point);
• Structural characterization; FTIR, UV/Vis, fluorescence, NMR, MS^n;
• Particle morphology, size and size distribution;
• Polymorph and salt screening;
• Solid state and solution stability;
• Drug-excipient compatibility and packaging component compatibility.